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Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defects
Prostate cancer (PCa) is a disease of mutated and misregulated genes. However, primary prostate tumors have relatively few mutations, and only three genes ( ERG, PTEN, and SPOP) are recurrently mutated in more than 10% of primary tumors. On the other hand, metastatic castration-resistant tumors have...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073096/ https://www.ncbi.nlm.nih.gov/pubmed/30135717 http://dx.doi.org/10.12688/f1000research.14499.1 |