Platinum Complexes Can Bind to Telomeres by Coordination

It is suggested that several compounds, including G-quadruplex ligands, can target telomeres, inducing their uncapping and, ultimately, cell death. However, it has never been demonstrated whether such ligands can bind directly and quantitatively to telomeres. Here, we employed the property of platin...

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Detalles Bibliográficos
Autores principales: Saker, Lina, Ali, Samar, Masserot, Caroline, Kellermann, Guillaume, Poupon, Joel, Teulade-Fichou, Marie-Paule, Ségal-Bendirdjian, Evelyne, Bombard, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073198/
https://www.ncbi.nlm.nih.gov/pubmed/29970863
http://dx.doi.org/10.3390/ijms19071951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073198/
https://www.ncbi.nlm.nih.gov/pubmed/29970863
http://dx.doi.org/10.3390/ijms19071951

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