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Platinum Complexes Can Bind to Telomeres by Coordination
It is suggested that several compounds, including G-quadruplex ligands, can target telomeres, inducing their uncapping and, ultimately, cell death. However, it has never been demonstrated whether such ligands can bind directly and quantitatively to telomeres. Here, we employed the property of platin...
Autores principales: | Saker, Lina, Ali, Samar, Masserot, Caroline, Kellermann, Guillaume, Poupon, Joel, Teulade-Fichou, Marie-Paule, Ségal-Bendirdjian, Evelyne, Bombard, Sophie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073198/ https://www.ncbi.nlm.nih.gov/pubmed/29970863 http://dx.doi.org/10.3390/ijms19071951 |
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