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Lithocholic Acid Is a Vitamin D Receptor Ligand That Acts Preferentially in the Ileum
The vitamin D receptor (VDR) is a nuclear receptor that mediates the biological action of the active form of vitamin D, 1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], and regulates calcium and bone metabolism. Lithocholic acid (LCA), which is a secondary bile acid produced by intestinal bacteria, ac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073204/ https://www.ncbi.nlm.nih.gov/pubmed/29986424 http://dx.doi.org/10.3390/ijms19071975 |