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Lithocholic Acid Is a Vitamin D Receptor Ligand That Acts Preferentially in the Ileum

The vitamin D receptor (VDR) is a nuclear receptor that mediates the biological action of the active form of vitamin D, 1α,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], and regulates calcium and bone metabolism. Lithocholic acid (LCA), which is a secondary bile acid produced by intestinal bacteria, ac...

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Detalles Bibliográficos
Autores principales:	Ishizawa, Michiyasu, Akagi, Daisuke, Makishima, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073204/ https://www.ncbi.nlm.nih.gov/pubmed/29986424 http://dx.doi.org/10.3390/ijms19071975

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