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Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity

Organometallic ruthenium(II) complexes [(η(6)-arene)Ru(en)Cl][PF(6)] (arene = benzene (1), p-cymene (2), indane (3), and biphenyl (4); en = ethylenediamine) are promising anticancer drug candidates both in vitro and in vivo. In this paper, the interactions between ruthenium(II) complexes and 15-mer...

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Detalles Bibliográficos
Autores principales: Liu, Suyan, Liang, Aihua, Wu, Kui, Zeng, Wenjuan, Luo, Qun, Wang, Fuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073332/
https://www.ncbi.nlm.nih.gov/pubmed/30041439
http://dx.doi.org/10.3390/ijms19072137

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