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Human 3D Cultures as Models for Evaluating Magnetic Nanoparticle CNS Cytotoxicity after Short- and Repeated Long-Term Exposure

Since nanoparticles (NPs) can translocate to the brain and impact the highly vulnerable central nervous system (CNS), novel in vitro tools for the assessment of NP-induced neurotoxicity are advocated. In this study, two types of CNS spheroids have been developed from human D384 astrocyte- and SH-SY5...

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Detalles Bibliográficos
Autores principales: De Simone, Uliana, Roccio, Marianna, Gribaldo, Laura, Spinillo, Arsenio, Caloni, Francesca, Coccini, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073335/
https://www.ncbi.nlm.nih.gov/pubmed/29986546
http://dx.doi.org/10.3390/ijms19071993