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Human 3D Cultures as Models for Evaluating Magnetic Nanoparticle CNS Cytotoxicity after Short- and Repeated Long-Term Exposure
Since nanoparticles (NPs) can translocate to the brain and impact the highly vulnerable central nervous system (CNS), novel in vitro tools for the assessment of NP-induced neurotoxicity are advocated. In this study, two types of CNS spheroids have been developed from human D384 astrocyte- and SH-SY5...
Autores principales: | De Simone, Uliana, Roccio, Marianna, Gribaldo, Laura, Spinillo, Arsenio, Caloni, Francesca, Coccini, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073335/ https://www.ncbi.nlm.nih.gov/pubmed/29986546 http://dx.doi.org/10.3390/ijms19071993 |
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