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Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study
Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073471/ https://www.ncbi.nlm.nih.gov/pubmed/29970834 http://dx.doi.org/10.3390/ijms19071949 |
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author | Holmer, Helene Widén, Cecilia Wallin Bengtsson, Viveca Coleman, Michael Wohlfart, Björn Steen, Stig Persson, Rutger Sjöberg, Klas |
author_facet | Holmer, Helene Widén, Cecilia Wallin Bengtsson, Viveca Coleman, Michael Wohlfart, Björn Steen, Stig Persson, Rutger Sjöberg, Klas |
author_sort | Holmer, Helene |
collection | PubMed |
description | Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND(®)). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND(®). The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND(®) (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND(®) thus showed significant promise in alleviating the impact of diabetes on dental as well as general health. |
format | Online Article Text |
id | pubmed-6073471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60734712018-08-13 Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study Holmer, Helene Widén, Cecilia Wallin Bengtsson, Viveca Coleman, Michael Wohlfart, Björn Steen, Stig Persson, Rutger Sjöberg, Klas Int J Mol Sci Article Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND(®)). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND(®). The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND(®) (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND(®) thus showed significant promise in alleviating the impact of diabetes on dental as well as general health. MDPI 2018-07-03 /pmc/articles/PMC6073471/ /pubmed/29970834 http://dx.doi.org/10.3390/ijms19071949 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Holmer, Helene Widén, Cecilia Wallin Bengtsson, Viveca Coleman, Michael Wohlfart, Björn Steen, Stig Persson, Rutger Sjöberg, Klas Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title | Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title_full | Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title_fullStr | Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title_full_unstemmed | Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title_short | Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study |
title_sort | improved general and oral health in diabetic patients by an okinawan-based nordic diet: a pilot study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073471/ https://www.ncbi.nlm.nih.gov/pubmed/29970834 http://dx.doi.org/10.3390/ijms19071949 |
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