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Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.)
We investigated the hypocholesterolemic and liver-protective effects of cooked and germinated whole mung beans. Hamsters were fed for 28 days on diets rich in saturated fatty acids and cholesterol, differing only in protein source (20%): casein, cooked whole mung bean, and germinated mung bean. Afte...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073478/ https://www.ncbi.nlm.nih.gov/pubmed/29949855 http://dx.doi.org/10.3390/nu10070821 |
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author | Lopes, Lays Arnaud Rosal Martins, Maria do Carmo de Carvalho e de Farias, Luciana Melo Brito, Ana Karolinne da Silva Lima, Geovanni de Morais de Carvalho, Vanessa Brito Lira Pereira, Cristian Francisco de Carvalho Conde Júnior, Aírton Mendes Saldanha, Tatiana Arêas, José Alfredo Gomes Silva, Kaesel Jackson Damasceno e Frota, Karoline de Macêdo Gonçalves |
author_facet | Lopes, Lays Arnaud Rosal Martins, Maria do Carmo de Carvalho e de Farias, Luciana Melo Brito, Ana Karolinne da Silva Lima, Geovanni de Morais de Carvalho, Vanessa Brito Lira Pereira, Cristian Francisco de Carvalho Conde Júnior, Aírton Mendes Saldanha, Tatiana Arêas, José Alfredo Gomes Silva, Kaesel Jackson Damasceno e Frota, Karoline de Macêdo Gonçalves |
author_sort | Lopes, Lays Arnaud Rosal |
collection | PubMed |
description | We investigated the hypocholesterolemic and liver-protective effects of cooked and germinated whole mung beans. Hamsters were fed for 28 days on diets rich in saturated fatty acids and cholesterol, differing only in protein source (20%): casein, cooked whole mung bean, and germinated mung bean. After 28 days, we found reduced plasma concentrations of total cholesterol and non-HDL cholesterol, increased faecal cholesterol excretion, and reduced levels of asparagine aminotransferase and alanine aminotransferase enzymes in the liver. Reduction in hepatic lipid deposition was observed between each of the mung bean groups relative to the casein group. In addition, the animals of the geminated mung bean group showed a lack of inflammatory infiltrate and better vascularisation of the hepatic tissue. Results from this study show significant hypocholesterolemic and liver-protective properties of the mung bean, which are further enhanced after germination. |
format | Online Article Text |
id | pubmed-6073478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60734782018-08-13 Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) Lopes, Lays Arnaud Rosal Martins, Maria do Carmo de Carvalho e de Farias, Luciana Melo Brito, Ana Karolinne da Silva Lima, Geovanni de Morais de Carvalho, Vanessa Brito Lira Pereira, Cristian Francisco de Carvalho Conde Júnior, Aírton Mendes Saldanha, Tatiana Arêas, José Alfredo Gomes Silva, Kaesel Jackson Damasceno e Frota, Karoline de Macêdo Gonçalves Nutrients Article We investigated the hypocholesterolemic and liver-protective effects of cooked and germinated whole mung beans. Hamsters were fed for 28 days on diets rich in saturated fatty acids and cholesterol, differing only in protein source (20%): casein, cooked whole mung bean, and germinated mung bean. After 28 days, we found reduced plasma concentrations of total cholesterol and non-HDL cholesterol, increased faecal cholesterol excretion, and reduced levels of asparagine aminotransferase and alanine aminotransferase enzymes in the liver. Reduction in hepatic lipid deposition was observed between each of the mung bean groups relative to the casein group. In addition, the animals of the geminated mung bean group showed a lack of inflammatory infiltrate and better vascularisation of the hepatic tissue. Results from this study show significant hypocholesterolemic and liver-protective properties of the mung bean, which are further enhanced after germination. MDPI 2018-06-26 /pmc/articles/PMC6073478/ /pubmed/29949855 http://dx.doi.org/10.3390/nu10070821 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lopes, Lays Arnaud Rosal Martins, Maria do Carmo de Carvalho e de Farias, Luciana Melo Brito, Ana Karolinne da Silva Lima, Geovanni de Morais de Carvalho, Vanessa Brito Lira Pereira, Cristian Francisco de Carvalho Conde Júnior, Aírton Mendes Saldanha, Tatiana Arêas, José Alfredo Gomes Silva, Kaesel Jackson Damasceno e Frota, Karoline de Macêdo Gonçalves Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title | Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title_full | Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title_fullStr | Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title_full_unstemmed | Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title_short | Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.) |
title_sort | cholesterol-lowering and liver-protective effects of cooked and germinated mung beans (vigna radiata l.) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073478/ https://www.ncbi.nlm.nih.gov/pubmed/29949855 http://dx.doi.org/10.3390/nu10070821 |
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