New Insights in Anti-Angiogenesis in Multiple Myeloma

Angiogenesis is a constant hallmark of multiple myeloma (MM) progression and involves direct production of angiogenic cytokines by plasma cells and their induction within the bone marrow microenvironment. This article summarizes the more recent literature data concerning the employment of anti-angio...

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Detalles Bibliográficos
Autores principales: Ribatti, Domenico, Vacca, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073492/
https://www.ncbi.nlm.nih.gov/pubmed/30002349
http://dx.doi.org/10.3390/ijms19072031
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author Ribatti, Domenico
Vacca, Angelo
author_facet Ribatti, Domenico
Vacca, Angelo
author_sort Ribatti, Domenico
collection PubMed
description Angiogenesis is a constant hallmark of multiple myeloma (MM) progression and involves direct production of angiogenic cytokines by plasma cells and their induction within the bone marrow microenvironment. This article summarizes the more recent literature data concerning the employment of anti-angiogenic therapeutic agents actually used in preclinical models and clinical settings for the treatment of multiple myeloma.
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spelling pubmed-60734922018-08-13 New Insights in Anti-Angiogenesis in Multiple Myeloma Ribatti, Domenico Vacca, Angelo Int J Mol Sci Review Angiogenesis is a constant hallmark of multiple myeloma (MM) progression and involves direct production of angiogenic cytokines by plasma cells and their induction within the bone marrow microenvironment. This article summarizes the more recent literature data concerning the employment of anti-angiogenic therapeutic agents actually used in preclinical models and clinical settings for the treatment of multiple myeloma. MDPI 2018-07-12 /pmc/articles/PMC6073492/ /pubmed/30002349 http://dx.doi.org/10.3390/ijms19072031 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ribatti, Domenico
Vacca, Angelo
New Insights in Anti-Angiogenesis in Multiple Myeloma
title New Insights in Anti-Angiogenesis in Multiple Myeloma
title_full New Insights in Anti-Angiogenesis in Multiple Myeloma
title_fullStr New Insights in Anti-Angiogenesis in Multiple Myeloma
title_full_unstemmed New Insights in Anti-Angiogenesis in Multiple Myeloma
title_short New Insights in Anti-Angiogenesis in Multiple Myeloma
title_sort new insights in anti-angiogenesis in multiple myeloma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073492/
https://www.ncbi.nlm.nih.gov/pubmed/30002349
http://dx.doi.org/10.3390/ijms19072031
work_keys_str_mv AT ribattidomenico newinsightsinantiangiogenesisinmultiplemyeloma
AT vaccaangelo newinsightsinantiangiogenesisinmultiplemyeloma

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