Cargando…
Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes
Gut derived bacterial endotoxins, such as lipopolysaccharide (LPS), are involved in one of the important mechanisms that lead to inflammation associated with various liver diseases, including nonalcoholic fatty liver disease and alcoholic liver disease. Kahweol is a coffee-specific diterpene present...
Autores principales: | Seo, Hye-Young, Kim, Mi-Kyung, Lee, So-Hee, Hwang, Jae Seok, Park, Keun-Gyu, Jang, Byoung Kuk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073512/ https://www.ncbi.nlm.nih.gov/pubmed/29973533 http://dx.doi.org/10.3390/nu10070863 |
Ejemplares similares
-
Kahweol Induces Apoptosis in Hepatocellular Carcinoma Cells by Inhibiting the Src/mTOR/STAT3 Signaling Pathway
por: Seo, Hye-Young, et al.
Publicado: (2021) -
Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway
por: Seo, Hye-Young, et al.
Publicado: (2017) -
Kahweol activates the Nrf2/HO-1 pathway by decreasing Keap1 expression independently of p62 and autophagy pathways
por: Seo, Hye-Young, et al.
Publicado: (2020) -
Kahweol Exerts Skin Moisturizing Activities by Upregulating STAT1 Activity
por: Chen, Hongxi, et al.
Publicado: (2021) -
Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice
por: Kim, Jung-Yeon, et al.
Publicado: (2020)