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Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii
Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes of the transsulfuration and de novo pathways f...
Autores principales: | Maresi, Elena, Janson, Giacomo, Fruncillo, Silvia, Paiardini, Alessandro, Vallone, Rosario, Dominici, Paola, Astegno, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073527/ https://www.ncbi.nlm.nih.gov/pubmed/30036991 http://dx.doi.org/10.3390/ijms19072111 |
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