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Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors

Carbonic anhydrase II (CAII) is a zinc-containing metalloenzyme whose aberrant activity is associated with various diseases such as glaucoma, osteoporosis, and different types of tumors; therefore, the development of CAII inhibitors, which can represent promising therapeutic agents for the treatment...

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Detalles Bibliográficos
Autores principales:	Poli, Giulio, Jha, Vibhu, Martinelli, Adriano, Supuran, Claudiu T., Tuccinardi, Tiziano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073570/ https://www.ncbi.nlm.nih.gov/pubmed/29937490 http://dx.doi.org/10.3390/ijms19071851

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