Cargando…
Targeting the NLRP3 Inflammasome-Related Pathways via Tianeptine Treatment-Suppressed Microglia Polarization to the M1 Phenotype in Lipopolysaccharide-Stimulated Cultures
An increasing body of evidence postulates that microglia are the main mediators of inflammation-related disorders, including depression. Since activated microglia produce a wide range of pro- and anti-inflammatory factors, the modulation of M1/M2 microglial polarization by antidepressants may be cru...
Autores principales: | Ślusarczyk, Joanna, Trojan, Ewa, Głombik, Katarzyna, Piotrowska, Anna, Budziszewska, Bogusława, Kubera, Marta, Popiołek-Barczyk, Katarzyna, Lasoń, Władysław, Mika, Joanna, Basta-Kaim, Agnieszka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073715/ https://www.ncbi.nlm.nih.gov/pubmed/29976873 http://dx.doi.org/10.3390/ijms19071965 |
Ejemplares similares
-
Prenatal stress is a vulnerability factor for altered morphology and biological activity of microglia cells
por: Ślusarczyk, Joanna, et al.
Publicado: (2015) -
The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression
por: Głombik, Katarzyna, et al.
Publicado: (2016) -
A new potential mechanism of action of tianeptine – the effect on microglial cell activation
por: Slusarczyk, Joanna, et al.
Publicado: (2015) -
The Beneficial Impact of Antidepressant Drugs on Prenatal Stress-Evoked Malfunction of the Insulin-Like Growth Factor-1 (IGF-1) Protein Family in the Olfactory Bulbs of Adult Rats
por: Trojan, Ewa, et al.
Publicado: (2015) -
Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress
por: Ślusarczyk, Joanna, et al.
Publicado: (2016)