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NR1 and NR3B Composed Intranuclear N-methyl-d-aspartate Receptor Complexes in Human Melanoma Cells

Heterotetrameric N-methyl-d-aspartate type glutamate receptors (NMDAR) are cationic channels primarily permeable for Ca(2+). NR1 and NR3 subunits bind glycine, while NR2 subunits bind glutamate for full activation. As NR1 may contain a nuclear localization signal (NLS) that is recognized by importin...

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Detalles Bibliográficos
Autores principales: Hajdú, Tibor, Juhász, Tamás, Szűcs-Somogyi, Csilla, Rácz, Kálmán, Zákány, Róza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073738/
https://www.ncbi.nlm.nih.gov/pubmed/29966365
http://dx.doi.org/10.3390/ijms19071929