FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1

In the rapidly developing field of targeted cancer therapy there is growing interest towards therapeutics combining two or more compounds to achieve synergistic action and minimize the chance of cancer resistance to treatment. We developed a fibroblast growth factor 2 (FGF2)-conjugate bearing two cy...

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Detalles Bibliográficos
Autores principales: Świderska, Karolina Weronika, Szlachcic, Anna, Opaliński, Łukasz, Zakrzewska, Małgorzata, Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073801/
https://www.ncbi.nlm.nih.gov/pubmed/30029518
http://dx.doi.org/10.3390/ijms19072098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073801/
https://www.ncbi.nlm.nih.gov/pubmed/30029518
http://dx.doi.org/10.3390/ijms19072098

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