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Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

The 11-member APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) family of zinc-dependent cytidine deaminases bind to RNA and single-stranded DNA (ssDNA) and, in specific contexts, modify select (deoxy)cytidines to (deoxy)uridines. In this review, we describe advances made through hig...

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Detalles Bibliográficos
Autores principales: Salter, Jason D., Smith, Harold C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073885/
https://www.ncbi.nlm.nih.gov/pubmed/29803538
http://dx.doi.org/10.1016/j.tibs.2018.04.013

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