The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

Gaucher disease is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Currently, enzyme-replacement therapy using recombinant GCase produced in mammalian cells is considered the most effective treatment. Plants are an attractive alternative host for recombinant protein production due t...

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Detalles Bibliográficos
Autores principales: Naphatsamon, Uthailak, Ohashi, Takao, Misaki, Ryo, Fujiyama, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073899/
https://www.ncbi.nlm.nih.gov/pubmed/29986415
http://dx.doi.org/10.3390/ijms19071972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073899/
https://www.ncbi.nlm.nih.gov/pubmed/29986415
http://dx.doi.org/10.3390/ijms19071972

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