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The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture
Gaucher disease is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Currently, enzyme-replacement therapy using recombinant GCase produced in mammalian cells is considered the most effective treatment. Plants are an attractive alternative host for recombinant protein production due t...
Autores principales: | Naphatsamon, Uthailak, Ohashi, Takao, Misaki, Ryo, Fujiyama, Kazuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073899/ https://www.ncbi.nlm.nih.gov/pubmed/29986415 http://dx.doi.org/10.3390/ijms19071972 |
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