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Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study

BACKGROUND: Genome-wide association studies have identified >30 common SNPs associated with epithelial ovarian cancer (EOC). We evaluated the combined effects of EOC susceptibility SNPs on predicting EOC risk in an independent prospective cohort study. METHODS: We genotyped ovarian cancer suscept...

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Detalles Bibliográficos
Autores principales:	Yang, Xin, Leslie, Goska, Gentry-Maharaj, Aleksandra, Ryan, Andy, Intermaggio, Maria, Lee, Andrew, Kalsi, Jatinderpal K, Tyrer, Jonathan, Gaba, Faiza, Manchanda, Ranjit, Pharoah, Paul D P, Gayther, Simon A, Ramus, Susan J, Jacobs, Ian, Menon, Usha, Antoniou, Antonis C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Cancer Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073911/ https://www.ncbi.nlm.nih.gov/pubmed/29730597 http://dx.doi.org/10.1136/jmedgenet-2018-105313

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