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The Curcumin Analog CH-5 Exerts Anticancer Effects in Human Osteosarcoma Cells via Modulation of Transcription Factors p53/Sp1

Curcumin is a potential anticancer drug with poor bioavailability, which limits its clinical use as a therapeutic agent. The aim of this study was a preliminary evaluation of the curcumin analogue CH-5 as a cytotoxic agent in human osteosarcoma cell lines U2OS, MG-63, and Saos-2. CH-5 inhibited cell...

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Detalles Bibliográficos
Autores principales:	Lima, Felipe Teixeira, Seba, Viviane, Silva, Gabriel, Torrezan, Guilherme Silva, Polaquini, Carlos Roberto, Pinhanelli, Vitor Caressato, Baek, Seung J., Fachin, Ana Lúcia, Regasini, Luis Octavio, Marins, Mozart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073932/ https://www.ncbi.nlm.nih.gov/pubmed/29966255 http://dx.doi.org/10.3390/ijms19071909

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