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Primary leiomyosarcoma of the atrium with heterologous differentiation
We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
King Faisal Specialist Hospital and Research Centre
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074192/ https://www.ncbi.nlm.nih.gov/pubmed/28988256 http://dx.doi.org/10.5144/0256-4947.2017.403 |
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author | Zaidi, Shaesta Husain, Sufia Barakah, Dona |
author_facet | Zaidi, Shaesta Husain, Sufia Barakah, Dona |
author_sort | Zaidi, Shaesta |
collection | PubMed |
description | We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive work-up, the mass was surgically resected. Histopathological findings from the acquired specimen revealed a high-grade leiomyosarcoma with extensive necrosis and heterologous (cartilaginous) differentiation. The early postoperative period was complicated by cardiac tamponade and the patient died on the second postoperative day due to ventricular arrhythmia, shock and multiorgan failure. |
format | Online Article Text |
id | pubmed-6074192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | King Faisal Specialist Hospital and Research Centre |
record_format | MEDLINE/PubMed |
spelling | pubmed-60741922018-09-21 Primary leiomyosarcoma of the atrium with heterologous differentiation Zaidi, Shaesta Husain, Sufia Barakah, Dona Ann Saudi Med Case Report We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive work-up, the mass was surgically resected. Histopathological findings from the acquired specimen revealed a high-grade leiomyosarcoma with extensive necrosis and heterologous (cartilaginous) differentiation. The early postoperative period was complicated by cardiac tamponade and the patient died on the second postoperative day due to ventricular arrhythmia, shock and multiorgan failure. King Faisal Specialist Hospital and Research Centre 2017 /pmc/articles/PMC6074192/ /pubmed/28988256 http://dx.doi.org/10.5144/0256-4947.2017.403 Text en Copyright © 2017, Annals of Saudi Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Case Report Zaidi, Shaesta Husain, Sufia Barakah, Dona Primary leiomyosarcoma of the atrium with heterologous differentiation |
title | Primary leiomyosarcoma of the atrium with heterologous differentiation |
title_full | Primary leiomyosarcoma of the atrium with heterologous differentiation |
title_fullStr | Primary leiomyosarcoma of the atrium with heterologous differentiation |
title_full_unstemmed | Primary leiomyosarcoma of the atrium with heterologous differentiation |
title_short | Primary leiomyosarcoma of the atrium with heterologous differentiation |
title_sort | primary leiomyosarcoma of the atrium with heterologous differentiation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074192/ https://www.ncbi.nlm.nih.gov/pubmed/28988256 http://dx.doi.org/10.5144/0256-4947.2017.403 |
work_keys_str_mv | AT zaidishaesta primaryleiomyosarcomaoftheatriumwithheterologousdifferentiation AT husainsufia primaryleiomyosarcomaoftheatriumwithheterologousdifferentiation AT barakahdona primaryleiomyosarcomaoftheatriumwithheterologousdifferentiation |