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Primary leiomyosarcoma of the atrium with heterologous differentiation

We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive w...

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Autores principales: Zaidi, Shaesta, Husain, Sufia, Barakah, Dona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074192/
https://www.ncbi.nlm.nih.gov/pubmed/28988256
http://dx.doi.org/10.5144/0256-4947.2017.403
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author Zaidi, Shaesta
Husain, Sufia
Barakah, Dona
author_facet Zaidi, Shaesta
Husain, Sufia
Barakah, Dona
author_sort Zaidi, Shaesta
collection PubMed
description We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive work-up, the mass was surgically resected. Histopathological findings from the acquired specimen revealed a high-grade leiomyosarcoma with extensive necrosis and heterologous (cartilaginous) differentiation. The early postoperative period was complicated by cardiac tamponade and the patient died on the second postoperative day due to ventricular arrhythmia, shock and multiorgan failure.
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spelling pubmed-60741922018-09-21 Primary leiomyosarcoma of the atrium with heterologous differentiation Zaidi, Shaesta Husain, Sufia Barakah, Dona Ann Saudi Med Case Report We report a case of a 47-year-old female who presented with breathlessness and palpitations for two weeks. On clinical evaluation, bilateral pedal edema was noticed. A CT pulmonary angiogram showed a mass in the left atrium causing significant obstruction to cardiovascular outflow. After extensive work-up, the mass was surgically resected. Histopathological findings from the acquired specimen revealed a high-grade leiomyosarcoma with extensive necrosis and heterologous (cartilaginous) differentiation. The early postoperative period was complicated by cardiac tamponade and the patient died on the second postoperative day due to ventricular arrhythmia, shock and multiorgan failure. King Faisal Specialist Hospital and Research Centre 2017 /pmc/articles/PMC6074192/ /pubmed/28988256 http://dx.doi.org/10.5144/0256-4947.2017.403 Text en Copyright © 2017, Annals of Saudi Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Case Report
Zaidi, Shaesta
Husain, Sufia
Barakah, Dona
Primary leiomyosarcoma of the atrium with heterologous differentiation
title Primary leiomyosarcoma of the atrium with heterologous differentiation
title_full Primary leiomyosarcoma of the atrium with heterologous differentiation
title_fullStr Primary leiomyosarcoma of the atrium with heterologous differentiation
title_full_unstemmed Primary leiomyosarcoma of the atrium with heterologous differentiation
title_short Primary leiomyosarcoma of the atrium with heterologous differentiation
title_sort primary leiomyosarcoma of the atrium with heterologous differentiation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074192/
https://www.ncbi.nlm.nih.gov/pubmed/28988256
http://dx.doi.org/10.5144/0256-4947.2017.403
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