Cargando…

Impact of exercise on oocyte quality in the POLG mitochondrial DNA mutator mouse

The mtDNA ‘mutator’ mouse, also called the ‘POLG’ mouse, is a well-characterized model frequently used for studies of progeroid aging. Harboring a mutation in the proofreading domain of the mitochondrial polymerase, polymerase-γ (Polg), POLG mice acquire mtDNA mutations at an accelerated rate. This...

Descripción completa

Detalles Bibliográficos
Autores principales:	Faraci, Christine, Annis, Sofia, Jin, Joyce, Li, Housaiyin, Khrapko, Konstantin, Woods, Dori C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074767/ https://www.ncbi.nlm.nih.gov/pubmed/29875308 http://dx.doi.org/10.1530/REP-18-0061

Ejemplares similares

Calorie restriction does not influence oocyte quality in oocytes from POLG mitochondrial mutator mice
por: Faraci, Christine, et al.
Publicado: (2018)

Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos
por: Woods, Dori C., et al.
Publicado: (2018)

A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics
por: MacDonald, Julie A., et al.
Publicado: (2019)

LUCS: a high-resolution nucleic acid sequencing tool for accurate long-read analysis of individual DNA molecules
por: Annis, Sofia, et al.
Publicado: (2020)

3GOLD: optimized Levenshtein distance for clustering third-generation sequencing data
por: Logan, Robert, et al.
Publicado: (2022)

Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome
por: Gunbin, Konstantin, et al.
Publicado: (2017)

The mtDNA mutation spectrum in the PolG mutator mouse reveals germline and somatic selection
por: Maclaine, Kendra D., et al.
Publicado: (2021)

Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties
por: Singh, Bhupendra, et al.
Publicado: (2015)

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice
por: Someya, Shinichi, et al.
Publicado: (2017)

Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations
por: Ashley, Neil, et al.
Publicado: (2008)

Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome
por: Hoff, Kirsten E., et al.
Publicado: (2018)

Deep sequencing of mitochondrial DNA and characterization of a novel POLG mutation in a patient with arPEO
por: Hedberg-Oldfors, Carola, et al.
Publicado: (2020)

Valproate Is Contraindicated in POLG1 Mutations
por: Finsterer, Josef
Publicado: (2019)

Quantification of mitochondrial DNA mutation load
por: Greaves, Laura C, et al.
Publicado: (2009)

Premature aging is associated with higher levels of 8‐oxoguanine and increased DNA damage in the Polg mutator mouse
por: Yu, Tenghui, et al.
Publicado: (2022)

Voluntary wheel running has no impact on brain and liver mitochondrial DNA copy number or mutation measures in the PolG mouse model of aging
por: Maclaine, Kendra D., et al.
Publicado: (2020)

Post-Translational Decrease in Respiratory Chain Proteins in the Polg Mutator Mouse Brain
por: Hauser, David N., et al.
Publicado: (2014)

Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors
por: Popadin, Konstantin, et al.
Publicado: (2022)

Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions
por: Fuke, Satoshi, et al.
Publicado: (2014)

Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice
por: Safdar, Adeel, et al.
Publicado: (2016)

The Y831C Mutation of the POLG Gene in Dementia
por: Borgione, Eugenia, et al.
Publicado: (2023)

Association of Mitochondrial DNA Polymerase γ Gene POLG1 Polymorphisms with Parkinsonism in Chinese Populations
por: Gui, Ya-xing, et al.
Publicado: (2012)

Interpreting Sequence-Levenshtein distance for determining error type and frequency between two embedded sequences of equal length
por: Logan, Robert, et al.
Publicado: (2023)

Retraction Note to: Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice
por: Safdar, Adeel, et al.
Publicado: (2021)

Progressive Ataxia and Palatal Tremor: Think about POLG Mutations
por: Mongin, Marie, et al.
Publicado: (2016)

Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts
por: Sitarz, Kamil S., et al.
Publicado: (2014)

POLG1-related Mitochondrial Disorder with MNGIE- and Leigh-like Features
por: Finsterer, Josef
Publicado: (2020)

Camptocormia as a Novel Phenotype in a Heterozygous POLG2 Mutation
por: Lehmann Urban, Diana, et al.
Publicado: (2020)

PPFIA4 mutation: A second hit in POLG related disease?
por: Sourbron, Jo, et al.
Publicado: (2021)

Enhancement of cranial nerves, conus medullaris, and nerve roots in POLG mitochondrial disease
por: Bayat, Michael, et al.
Publicado: (2019)

Diagnosing mitochondrial, neurogastrointestinal leukoencephalopathy requires mutations in TYMP1, POLG1, LIG1, or RRM2B
por: Finsterer, Josef
Publicado: (2023)

Understanding the Epilepsy in POLG Related Disease
por: Hikmat, Omar, et al.
Publicado: (2017)

A new pathogenic POLG variant
por: Nicholas Russo, S., et al.
Publicado: (2022)

Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation
por: Medeiros, Tânia Catarina, et al.
Publicado: (2018)

PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance
por: Wen, Jake Jianjun, et al.
Publicado: (2018)

Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome
por: Schaller, André, et al.
Publicado: (2011)

Recurrent major depression, ataxia, and cardiomyopathy: association with a novel POLG mutation?
por: Verhoeven, Willem MA, et al.
Publicado: (2011)

Magnesium treatment for patients with refractory status epilepticus due to POLG1-mutations
por: Visser, Nora A., et al.
Publicado: (2010)

Ketogenic diet in a patient with refractory status epilepticus due to POLG mutation
por: Koessler, Miriam, et al.
Publicado: (2020)

Dystonia Responsive to Dopamine: POLG Mutations Should Be Considered If Sensory Neuropathy Is Present
por: Qiu, Jessica, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6bnm9960c519obtdmpekprd03b