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Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study

BACKGROUND: The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. METHODS: A total of 16,292 CP patients and 48,876 randomly-selected controls without chronic periodontitis...

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Autores principales: Huang, I-Shen, Huang, Sung-En, Kao, Wei-Tang, Chiang, Cheng-Yen, Chang, To, Lin, Cheng-I, Lin, Alex T., Lin, Chih-Chieh, Fan, Yu-Hua, Chung, Hsiao-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074789/
https://www.ncbi.nlm.nih.gov/pubmed/30083446
http://dx.doi.org/10.7717/peerj.5287
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author Huang, I-Shen
Huang, Sung-En
Kao, Wei-Tang
Chiang, Cheng-Yen
Chang, To
Lin, Cheng-I
Lin, Alex T.
Lin, Chih-Chieh
Fan, Yu-Hua
Chung, Hsiao-Jen
author_facet Huang, I-Shen
Huang, Sung-En
Kao, Wei-Tang
Chiang, Cheng-Yen
Chang, To
Lin, Cheng-I
Lin, Alex T.
Lin, Chih-Chieh
Fan, Yu-Hua
Chung, Hsiao-Jen
author_sort Huang, I-Shen
collection PubMed
description BACKGROUND: The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. METHODS: A total of 16,292 CP patients and 48,876 randomly-selected controls without chronic periodontitis were selected from the National research database and studied retrospectively. Subjects selected have not been diagnosed with UUTS previously. These subjects were prospectively followed for at least eight years. Cox regression models were used to explore the connection between risk factors and the development of UUTS. RESULTS: The CP patients have a greater chance of developing UUTS compared to controls (1761/16292, 10.8% vs. 4775/48876, 9.8%, p-values < 0.001). Conditioned logistic regression suggested CP increases the risk of UUTS development (HR 1.14, 95% CI [1.08–1.20], p < 0.001). After respective adjustment for age, gender, hypertension and diabetes, results showed that CP still increases the risk of developing UUTS (HR 1.14, 95% CI [1.08–1.20], p < 0.001). CONCLUSION: By using a population-based database with a minimum eight 8 follow-up of CP in Taiwan, we discovered patients with CP are more likely to develop UUTS.
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spelling pubmed-60747892018-08-06 Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study Huang, I-Shen Huang, Sung-En Kao, Wei-Tang Chiang, Cheng-Yen Chang, To Lin, Cheng-I Lin, Alex T. Lin, Chih-Chieh Fan, Yu-Hua Chung, Hsiao-Jen PeerJ Dentistry BACKGROUND: The purpose of this study was to investigate the relationship between chronic periodontitis (CP) and upper urinary tract stone (UUTS) in Taiwan by using a population-based data set. METHODS: A total of 16,292 CP patients and 48,876 randomly-selected controls without chronic periodontitis were selected from the National research database and studied retrospectively. Subjects selected have not been diagnosed with UUTS previously. These subjects were prospectively followed for at least eight years. Cox regression models were used to explore the connection between risk factors and the development of UUTS. RESULTS: The CP patients have a greater chance of developing UUTS compared to controls (1761/16292, 10.8% vs. 4775/48876, 9.8%, p-values < 0.001). Conditioned logistic regression suggested CP increases the risk of UUTS development (HR 1.14, 95% CI [1.08–1.20], p < 0.001). After respective adjustment for age, gender, hypertension and diabetes, results showed that CP still increases the risk of developing UUTS (HR 1.14, 95% CI [1.08–1.20], p < 0.001). CONCLUSION: By using a population-based database with a minimum eight 8 follow-up of CP in Taiwan, we discovered patients with CP are more likely to develop UUTS. PeerJ Inc. 2018-07-31 /pmc/articles/PMC6074789/ /pubmed/30083446 http://dx.doi.org/10.7717/peerj.5287 Text en ©2018 Huang et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Dentistry
Huang, I-Shen
Huang, Sung-En
Kao, Wei-Tang
Chiang, Cheng-Yen
Chang, To
Lin, Cheng-I
Lin, Alex T.
Lin, Chih-Chieh
Fan, Yu-Hua
Chung, Hsiao-Jen
Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title_full Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title_fullStr Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title_full_unstemmed Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title_short Patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
title_sort patients with chronic periodontitis are more likely to develop upper urinary tract stone: a nation-wide population-based eight-year follow up study
topic Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074789/
https://www.ncbi.nlm.nih.gov/pubmed/30083446
http://dx.doi.org/10.7717/peerj.5287
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