Metformin induces miR-378 to downregulate the CDK1, leading to suppression of cell proliferation in hepatocellular carcinoma

Metformin is one of the extensively and most commonly used oral antihyperglycemic agents, but it has been shown to exert antineoplastic effects in many cancer cells. Recent studies have confirmed that metformin has an antitumor effect on hepatocellular carcinoma (HCC). However, the molecular mechani...

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Detalles Bibliográficos
Autores principales: Zhou, Jin, Han, Sheng, Qian, Weichun, Gu, Yuanyuan, Li, Xiangcheng, Yang, Kunxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074828/
https://www.ncbi.nlm.nih.gov/pubmed/30104887
http://dx.doi.org/10.2147/OTT.S167614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074828/
https://www.ncbi.nlm.nih.gov/pubmed/30104887
http://dx.doi.org/10.2147/OTT.S167614

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