Clear cell myoepithelioma of the hard palate

Clear cell myoepithelioma arising from the minor salivary glands of hard palate is a rare entity. Most of the cases of palatal myoepitheliomas reported so far are either plasmacytoid or spindle cell type. Our literature search revealed only one case report of clear cell myoepithelioma of the palate. We report a case in a 21-year-old female who presented to us with a non-ulcerating, painless firm swelling of the left side of the hard palate. The tumor was excised with a healthy rim of surrounding tissue. Immunohistochemistry was performed on formalin-fixed and paraffin-embedded tissue with a panel of immunohistochemical markers. Tumor cells showed positivity for S100, cytokeratin and Muscle specific actin. Histological and immunohistochemical analyses revealed the tumor to be a myoepithelioma of the clear cell variety.