Cargando…

Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair

Botulinum toxin is a neurotoxin that has been utilized to induce chemo-denervation of muscles. Cutaneous wounds represent a special situation in which the tensile forces applied by these muscles on wound edges might have deleterious effects on the healing process. The aim of this review was to inves...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Qattan, Mohammad M., Al-Shanawani, Bisher Nawras, Alshomer, Feras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074896/
https://www.ncbi.nlm.nih.gov/pubmed/24188943
http://dx.doi.org/10.5144/0256-4947.2013.482
_version_ 1783344504596594688
author Al-Qattan, Mohammad M.
Al-Shanawani, Bisher Nawras
Alshomer, Feras
author_facet Al-Qattan, Mohammad M.
Al-Shanawani, Bisher Nawras
Alshomer, Feras
author_sort Al-Qattan, Mohammad M.
collection PubMed
description Botulinum toxin is a neurotoxin that has been utilized to induce chemo-denervation of muscles. Cutaneous wounds represent a special situation in which the tensile forces applied by these muscles on wound edges might have deleterious effects on the healing process. The aim of this review was to investigate such an effect and to review other mechanisms this toxin might have on the healing process. We also reviewed the role of botulinum toxin in the management of hypertrophic scars and cleft lip repair.
format Online
Article
Text
id pubmed-6074896
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher King Faisal Specialist Hospital and Research Centre
record_format MEDLINE/PubMed
spelling pubmed-60748962018-09-21 Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair Al-Qattan, Mohammad M. Al-Shanawani, Bisher Nawras Alshomer, Feras Ann Saudi Med Review Botulinum toxin is a neurotoxin that has been utilized to induce chemo-denervation of muscles. Cutaneous wounds represent a special situation in which the tensile forces applied by these muscles on wound edges might have deleterious effects on the healing process. The aim of this review was to investigate such an effect and to review other mechanisms this toxin might have on the healing process. We also reviewed the role of botulinum toxin in the management of hypertrophic scars and cleft lip repair. King Faisal Specialist Hospital and Research Centre 2013 /pmc/articles/PMC6074896/ /pubmed/24188943 http://dx.doi.org/10.5144/0256-4947.2013.482 Text en Copyright © 2013, Annals of Saudi Medicine This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review
Al-Qattan, Mohammad M.
Al-Shanawani, Bisher Nawras
Alshomer, Feras
Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title_full Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title_fullStr Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title_full_unstemmed Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title_short Botulinum toxin type A: implications in wound healing, facial cutaneous scarring, and cleft lip repair
title_sort botulinum toxin type a: implications in wound healing, facial cutaneous scarring, and cleft lip repair
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074896/
https://www.ncbi.nlm.nih.gov/pubmed/24188943
http://dx.doi.org/10.5144/0256-4947.2013.482
work_keys_str_mv AT alqattanmohammadm botulinumtoxintypeaimplicationsinwoundhealingfacialcutaneousscarringandcleftliprepair
AT alshanawanibishernawras botulinumtoxintypeaimplicationsinwoundhealingfacialcutaneousscarringandcleftliprepair
AT alshomerferas botulinumtoxintypeaimplicationsinwoundhealingfacialcutaneousscarringandcleftliprepair