Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly

In Schizosaccharomyces pombe, transcripts derived from the pericentromeric dg and dh repeats promote heterochromatin formation via RNAi as well as an RNAi-independent mechanism involving the RNA polymerase II (RNAPII)-associated RNA-binding protein Seb1 and RNA processing activities. We show that Se...

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Detalles Bibliográficos
Autores principales: Parsa, Jahan-Yar, Boudoukha, Selim, Burke, Jordan, Homer, Christina, Madhani, Hiten D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075038/
https://www.ncbi.nlm.nih.gov/pubmed/29967291
http://dx.doi.org/10.1101/gad.310136.117

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