PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is known to regulate lipid metabolism in many tissues, including macrophages. Here we report that peritoneal macrophage respiration is enhanced by rosiglitazone, an activating PPARγ ligand, in a PPARγ-dependent manner. Moreove...

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Detalles Bibliográficos
Autores principales: Nelson, Victoria L., Nguyen, Hoang C.B., Garcìa-Cañaveras, Juan C., Briggs, Erika R., Ho, Wesley Y., DiSpirito, Joanna R., Marinis, Jill M., Hill, David A., Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075146/
https://www.ncbi.nlm.nih.gov/pubmed/30006480
http://dx.doi.org/10.1101/gad.312355.118

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