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A set of conformationally well-defined L/D-peptide epitopes provides a serological bar code for autoantibody subtypes

Which conformational parameters lead to an antibody-affine peptide antigen? And in how many different conformations can we actually present the respective conformational epitope? To provide answers from a chemical point of view, we direct the bending and tethering of peptide backbones by the utilisa...

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Detalles Bibliográficos
Autores principales: Schrimpf, Andreas, Brödje, Dörte, Pfefferle, Petra, Geyer, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075753/
https://www.ncbi.nlm.nih.gov/pubmed/30075018
http://dx.doi.org/10.1371/journal.pone.0201735

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