How does binding of agonist ligands control intrinsic molecular dynamics in human NMDA receptors?

NMDA-type glutamate receptors (NMDAR) are ligand-gated ion channels that contribute to excitatory neurotransmission in the central nervous system. NMDAR dysfunction has been found to be involved in various neurological disorders. Recent crystallographic and EM studies have shown the static structure...

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Detalles Bibliográficos
Autores principales: Palmai, Zoltan, Houenoussi, Kimberley, Cohen-Kaminsky, Sylvia, Tchertanov, Luba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075769/
https://www.ncbi.nlm.nih.gov/pubmed/30075003
http://dx.doi.org/10.1371/journal.pone.0201234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075769/
https://www.ncbi.nlm.nih.gov/pubmed/30075003
http://dx.doi.org/10.1371/journal.pone.0201234

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