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How does binding of agonist ligands control intrinsic molecular dynamics in human NMDA receptors?
NMDA-type glutamate receptors (NMDAR) are ligand-gated ion channels that contribute to excitatory neurotransmission in the central nervous system. NMDAR dysfunction has been found to be involved in various neurological disorders. Recent crystallographic and EM studies have shown the static structure...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075769/ https://www.ncbi.nlm.nih.gov/pubmed/30075003 http://dx.doi.org/10.1371/journal.pone.0201234 |