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A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system
BACKGROUND: This study presents a novel methodology for estimating all-age, population-based incidence rates of norovirus and other pathogens that contribute to acute gastroenteritis in the United States using an integrated healthcare delivery system as a surveillance platform. METHODS: All cases of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075775/ https://www.ncbi.nlm.nih.gov/pubmed/30075030 http://dx.doi.org/10.1371/journal.pone.0201805 |
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author | Schmidt, Mark A. Groom, Holly C. Naleway, Allison L. Biggs, Christianne Salas, S. Bianca Shioda, Kayoko Marsh, Zachary Donald, Judy L. Hall, Aron J. |
author_facet | Schmidt, Mark A. Groom, Holly C. Naleway, Allison L. Biggs, Christianne Salas, S. Bianca Shioda, Kayoko Marsh, Zachary Donald, Judy L. Hall, Aron J. |
author_sort | Schmidt, Mark A. |
collection | PubMed |
description | BACKGROUND: This study presents a novel methodology for estimating all-age, population-based incidence rates of norovirus and other pathogens that contribute to acute gastroenteritis in the United States using an integrated healthcare delivery system as a surveillance platform. METHODS: All cases of medically attended acute gastroenteritis within the delivery system were identified from April 1, 2014 through September 30, 2016. A sample of these eligible patients were selected to participate in two phone-based surveys and to self-collect a stool sample for laboratory testing. To ascertain household transmission patterns, information on household members with acute gastroenteritis was gathered from participants, and symptomatic household members were contacted to participate in a survey and provide stool sample as well. RESULTS: 54% of individuals who met enrollment criteria agreed to participate, and 76% of those individuals returned a stool sample. Among household members, 85% of eligible individuals agreed to participate, and 68% of those returned a stool sample. Participant demographics were similar to those of the eligible population, although minority racial/ethnic groups were somewhat underrepresented in the final sample. CONCLUSIONS: This study demonstrates the feasibility of conducting acute infectious disease research within an integrated health care delivery system. The surveillance, sampling, recruitment, and data collection methods described here are broadly applicable to conduct baseline and epidemiological assessments, as well as for other research requiring representative samples of stool specimens. |
format | Online Article Text |
id | pubmed-6075775 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-60757752018-08-28 A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system Schmidt, Mark A. Groom, Holly C. Naleway, Allison L. Biggs, Christianne Salas, S. Bianca Shioda, Kayoko Marsh, Zachary Donald, Judy L. Hall, Aron J. PLoS One Research Article BACKGROUND: This study presents a novel methodology for estimating all-age, population-based incidence rates of norovirus and other pathogens that contribute to acute gastroenteritis in the United States using an integrated healthcare delivery system as a surveillance platform. METHODS: All cases of medically attended acute gastroenteritis within the delivery system were identified from April 1, 2014 through September 30, 2016. A sample of these eligible patients were selected to participate in two phone-based surveys and to self-collect a stool sample for laboratory testing. To ascertain household transmission patterns, information on household members with acute gastroenteritis was gathered from participants, and symptomatic household members were contacted to participate in a survey and provide stool sample as well. RESULTS: 54% of individuals who met enrollment criteria agreed to participate, and 76% of those individuals returned a stool sample. Among household members, 85% of eligible individuals agreed to participate, and 68% of those returned a stool sample. Participant demographics were similar to those of the eligible population, although minority racial/ethnic groups were somewhat underrepresented in the final sample. CONCLUSIONS: This study demonstrates the feasibility of conducting acute infectious disease research within an integrated health care delivery system. The surveillance, sampling, recruitment, and data collection methods described here are broadly applicable to conduct baseline and epidemiological assessments, as well as for other research requiring representative samples of stool specimens. Public Library of Science 2018-08-03 /pmc/articles/PMC6075775/ /pubmed/30075030 http://dx.doi.org/10.1371/journal.pone.0201805 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
spellingShingle | Research Article Schmidt, Mark A. Groom, Holly C. Naleway, Allison L. Biggs, Christianne Salas, S. Bianca Shioda, Kayoko Marsh, Zachary Donald, Judy L. Hall, Aron J. A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title | A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title_full | A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title_fullStr | A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title_full_unstemmed | A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title_short | A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
title_sort | model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075775/ https://www.ncbi.nlm.nih.gov/pubmed/30075030 http://dx.doi.org/10.1371/journal.pone.0201805 |
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