Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer

BACKGROUND: First line chemotherapy is effective in 75 to 80% of patients with metastatic colorectal cancer (mCRC). We studied whether microRNA (miR) expression profiles can predict treatment outcome for first line fluoropyrimidine containing systemic therapy in patients with mCRC. METHODS: MiR expr...

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Detalles Bibliográficos
Autores principales: Neerincx, Maarten, Poel, Dennis, Sie, Daoud L. S., van Grieken, Nicole C. T., Shankaraiah, Ram C., van der Wolf - de Lijster, Floor S. W., van Waesberghe, Jan-Hein T. M., Burggraaf, Jan-Dirk, Eijk, Paul P., Verhoef, Cornelis, Ylstra, Bauke, Meijer, Gerrit A., van de Wiel, Mark A., Buffart, Tineke E., Verheul, Henk M. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075783/
https://www.ncbi.nlm.nih.gov/pubmed/30075027
http://dx.doi.org/10.1371/journal.pone.0201809

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