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NF-κB activation is an early event of changes in gene regulation for acquiring drug resistance in human adenocarcinoma PC-9 cells

Gefitinib and erlotinib are epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Although EGFR-TKIs are effective as anti-cancer drugs, cancer cells sometimes gain tolerance to the drugs. Previous studies suggested that the fibroblast growth factor receptor (FGFR)-signaling pathw...

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Detalles Bibliográficos
Autores principales:	Fukuoka, Masashi, Yoshioka, Katsuji, Hohjoh, Hirohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075786/ https://www.ncbi.nlm.nih.gov/pubmed/30075033 http://dx.doi.org/10.1371/journal.pone.0201796

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