Pharmacokinetics of Doripenem in Healthy Koreans and Monte Carlo Simulations to Explore Optimal Dosage Regimens in Patients With Normal and Enhanced Renal Function

BACKGROUND: Dose adjustment is often required in patients with normal or enhanced renal function. The aim of this study is to investigate the pharmacokinetic (PK) properties of doripenem and explore optimal dosing regimens in patients with normal or enhanced renal function according to various minim...

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Detalles Bibliográficos
Autores principales: Kim, So Won, Choe, Sangmin, Kim, Dong Jin, Zang, Dae Young, Lee, Dong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075885/
https://www.ncbi.nlm.nih.gov/pubmed/29746394
http://dx.doi.org/10.1097/FTD.0000000000000528

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