Cargando…

Sellar chondrosarcoma presenting with amenorrhea: A case report

RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CON...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Junguo, Li, Guihong, Sun, Yuxue, Hong, Xinyu, Huang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076023/
https://www.ncbi.nlm.nih.gov/pubmed/29979394
http://dx.doi.org/10.1097/MD.0000000000011274
_version_ 1783344630185590784
author Cao, Junguo
Li, Guihong
Sun, Yuxue
Hong, Xinyu
Huang, Haiyan
author_facet Cao, Junguo
Li, Guihong
Sun, Yuxue
Hong, Xinyu
Huang, Haiyan
author_sort Cao, Junguo
collection PubMed
description RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CONCERNS: A 45-year-old woman presented with a 7-month history of amenorrhea and a 3-month history of progressive visual loss in the left eye. DIAGNOSIS: The patient was diagnosed with recurrent sellar chondrosarcoma arising from intrasellar with extensive tumor invasion into bilateral sphenoid sinuses. INTERVENTIONS: Twice endonasal transsphenoidal tumorectomies were performed followed with a stereotactic radiotherapy and hormone replacement therapy. OUTCOMES: The patient's condition was stable and her visual symptoms improved, the hormones returned to normal, and no recurrence was noted on MRI after six months. LESSONS: Sellar chondrosarcomas with the onset of endocrine dysfunctions are extremely rare, which may be misdiagnosed as pituitary adenoma and the definitive diagnosis depends on histopathological and immunohistochemical evidence. The first choice of treatment is surgery with the goal of complete resection, and postoperative adjuvant radiotherapy should be highlighted.
format Online
Article
Text
id pubmed-6076023
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-60760232018-08-13 Sellar chondrosarcoma presenting with amenorrhea: A case report Cao, Junguo Li, Guihong Sun, Yuxue Hong, Xinyu Huang, Haiyan Medicine (Baltimore) Research Article RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CONCERNS: A 45-year-old woman presented with a 7-month history of amenorrhea and a 3-month history of progressive visual loss in the left eye. DIAGNOSIS: The patient was diagnosed with recurrent sellar chondrosarcoma arising from intrasellar with extensive tumor invasion into bilateral sphenoid sinuses. INTERVENTIONS: Twice endonasal transsphenoidal tumorectomies were performed followed with a stereotactic radiotherapy and hormone replacement therapy. OUTCOMES: The patient's condition was stable and her visual symptoms improved, the hormones returned to normal, and no recurrence was noted on MRI after six months. LESSONS: Sellar chondrosarcomas with the onset of endocrine dysfunctions are extremely rare, which may be misdiagnosed as pituitary adenoma and the definitive diagnosis depends on histopathological and immunohistochemical evidence. The first choice of treatment is surgery with the goal of complete resection, and postoperative adjuvant radiotherapy should be highlighted. Wolters Kluwer Health 2018-07-06 /pmc/articles/PMC6076023/ /pubmed/29979394 http://dx.doi.org/10.1097/MD.0000000000011274 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Research Article
Cao, Junguo
Li, Guihong
Sun, Yuxue
Hong, Xinyu
Huang, Haiyan
Sellar chondrosarcoma presenting with amenorrhea: A case report
title Sellar chondrosarcoma presenting with amenorrhea: A case report
title_full Sellar chondrosarcoma presenting with amenorrhea: A case report
title_fullStr Sellar chondrosarcoma presenting with amenorrhea: A case report
title_full_unstemmed Sellar chondrosarcoma presenting with amenorrhea: A case report
title_short Sellar chondrosarcoma presenting with amenorrhea: A case report
title_sort sellar chondrosarcoma presenting with amenorrhea: a case report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076023/
https://www.ncbi.nlm.nih.gov/pubmed/29979394
http://dx.doi.org/10.1097/MD.0000000000011274
work_keys_str_mv AT caojunguo sellarchondrosarcomapresentingwithamenorrheaacasereport
AT liguihong sellarchondrosarcomapresentingwithamenorrheaacasereport
AT sunyuxue sellarchondrosarcomapresentingwithamenorrheaacasereport
AT hongxinyu sellarchondrosarcomapresentingwithamenorrheaacasereport
AT huanghaiyan sellarchondrosarcomapresentingwithamenorrheaacasereport