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Sellar chondrosarcoma presenting with amenorrhea: A case report
RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CON...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076023/ https://www.ncbi.nlm.nih.gov/pubmed/29979394 http://dx.doi.org/10.1097/MD.0000000000011274 |
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author | Cao, Junguo Li, Guihong Sun, Yuxue Hong, Xinyu Huang, Haiyan |
author_facet | Cao, Junguo Li, Guihong Sun, Yuxue Hong, Xinyu Huang, Haiyan |
author_sort | Cao, Junguo |
collection | PubMed |
description | RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CONCERNS: A 45-year-old woman presented with a 7-month history of amenorrhea and a 3-month history of progressive visual loss in the left eye. DIAGNOSIS: The patient was diagnosed with recurrent sellar chondrosarcoma arising from intrasellar with extensive tumor invasion into bilateral sphenoid sinuses. INTERVENTIONS: Twice endonasal transsphenoidal tumorectomies were performed followed with a stereotactic radiotherapy and hormone replacement therapy. OUTCOMES: The patient's condition was stable and her visual symptoms improved, the hormones returned to normal, and no recurrence was noted on MRI after six months. LESSONS: Sellar chondrosarcomas with the onset of endocrine dysfunctions are extremely rare, which may be misdiagnosed as pituitary adenoma and the definitive diagnosis depends on histopathological and immunohistochemical evidence. The first choice of treatment is surgery with the goal of complete resection, and postoperative adjuvant radiotherapy should be highlighted. |
format | Online Article Text |
id | pubmed-6076023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-60760232018-08-13 Sellar chondrosarcoma presenting with amenorrhea: A case report Cao, Junguo Li, Guihong Sun, Yuxue Hong, Xinyu Huang, Haiyan Medicine (Baltimore) Research Article RATIONALE: Intracranial chondrosarcomas are rare entities and most of which arise off the midline. Chondrosarcomas that occur in the sellar region are extremely rare, and to the best of our knowledge, there is no reporting about sellar chondrosarcoma with amenorrhea as the onset symptom. PATIENT CONCERNS: A 45-year-old woman presented with a 7-month history of amenorrhea and a 3-month history of progressive visual loss in the left eye. DIAGNOSIS: The patient was diagnosed with recurrent sellar chondrosarcoma arising from intrasellar with extensive tumor invasion into bilateral sphenoid sinuses. INTERVENTIONS: Twice endonasal transsphenoidal tumorectomies were performed followed with a stereotactic radiotherapy and hormone replacement therapy. OUTCOMES: The patient's condition was stable and her visual symptoms improved, the hormones returned to normal, and no recurrence was noted on MRI after six months. LESSONS: Sellar chondrosarcomas with the onset of endocrine dysfunctions are extremely rare, which may be misdiagnosed as pituitary adenoma and the definitive diagnosis depends on histopathological and immunohistochemical evidence. The first choice of treatment is surgery with the goal of complete resection, and postoperative adjuvant radiotherapy should be highlighted. Wolters Kluwer Health 2018-07-06 /pmc/articles/PMC6076023/ /pubmed/29979394 http://dx.doi.org/10.1097/MD.0000000000011274 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | Research Article Cao, Junguo Li, Guihong Sun, Yuxue Hong, Xinyu Huang, Haiyan Sellar chondrosarcoma presenting with amenorrhea: A case report |
title | Sellar chondrosarcoma presenting with amenorrhea: A case report |
title_full | Sellar chondrosarcoma presenting with amenorrhea: A case report |
title_fullStr | Sellar chondrosarcoma presenting with amenorrhea: A case report |
title_full_unstemmed | Sellar chondrosarcoma presenting with amenorrhea: A case report |
title_short | Sellar chondrosarcoma presenting with amenorrhea: A case report |
title_sort | sellar chondrosarcoma presenting with amenorrhea: a case report |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076023/ https://www.ncbi.nlm.nih.gov/pubmed/29979394 http://dx.doi.org/10.1097/MD.0000000000011274 |
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