In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles

Glycoproteins secreted by helminth parasites are immunogenic and represent appealing components of vaccine preparations. Our poor knowledge of the pathways that mediate protein glycosylation in parasitic flatworms hinders our understanding of how proteins are synthesised and modified, and our abilit...

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Detalles Bibliográficos
Autores principales: McVeigh, Paul, Cwiklinski, Krystyna, Garcia-Campos, Andres, Mulcahy, Grace, O’Neill, Sandra M., Maule, Aaron G., Dalton, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076252/
https://www.ncbi.nlm.nih.gov/pubmed/30076319
http://dx.doi.org/10.1038/s41598-018-29673-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076252/
https://www.ncbi.nlm.nih.gov/pubmed/30076319
http://dx.doi.org/10.1038/s41598-018-29673-3

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