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In silico analyses of protein glycosylating genes in the helminth Fasciola hepatica (liver fluke) predict protein-linked glycan simplicity and reveal temporally-dynamic expression profiles
Glycoproteins secreted by helminth parasites are immunogenic and represent appealing components of vaccine preparations. Our poor knowledge of the pathways that mediate protein glycosylation in parasitic flatworms hinders our understanding of how proteins are synthesised and modified, and our abilit...
Autores principales: | McVeigh, Paul, Cwiklinski, Krystyna, Garcia-Campos, Andres, Mulcahy, Grace, O’Neill, Sandra M., Maule, Aaron G., Dalton, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076252/ https://www.ncbi.nlm.nih.gov/pubmed/30076319 http://dx.doi.org/10.1038/s41598-018-29673-3 |
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