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Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat
In order to provide timely treatment for organ damage initiated by therapeutic drugs or exposure to environmental toxicants, we first need to identify markers that provide an early diagnosis of potential adverse effects before permanent damage occurs. Specifically, the liver, as a primary organ pron...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076258/ https://www.ncbi.nlm.nih.gov/pubmed/30076366 http://dx.doi.org/10.1038/s41598-018-30149-7 |