Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat

In order to provide timely treatment for organ damage initiated by therapeutic drugs or exposure to environmental toxicants, we first need to identify markers that provide an early diagnosis of potential adverse effects before permanent damage occurs. Specifically, the liver, as a primary organ pron...

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Detalles Bibliográficos
Autores principales: Pannala, Venkat R., Wall, Martha L., Estes, Shanea K., Trenary, Irina, O’Brien, Tracy P., Printz, Richard L., Vinnakota, Kalyan C., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076258/
https://www.ncbi.nlm.nih.gov/pubmed/30076366
http://dx.doi.org/10.1038/s41598-018-30149-7

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