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AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart

The RNA-binding protein Rbm24 has recently been identified as a pivotal splicing factor in the developing heart. Loss of Rbm24 in mice disrupts cardiac development by governing a large number of muscle-specific splicing events. Since Rbm24 knockout mice are embryonically lethal, the role of Rbm24 in...

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Detalles Bibliográficos
Autores principales:	van den Hoogenhof, Maarten M. G., van der Made, Ingeborg, de Groot, Nina E., Damanafshan, Amin, van Amersfoorth, Shirley C. M., Zentilin, Lorena, Giacca, Mauro, Pinto, Yigal M., Creemers, Esther E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076270/ https://www.ncbi.nlm.nih.gov/pubmed/30076363 http://dx.doi.org/10.1038/s41598-018-29552-x

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