Cargando…

Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative

Saccharomyces cerevisiae is a Crabtree-positive eukaryal model organism. It is believed that the Crabtree effect has evolved as a competition mechanism by allowing for rapid growth and production of ethanol at aerobic glucose excess conditions. This inherent property of yeast metabolism and the mult...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Zongjie, Huang, Mingtao, Chen, Yun, Siewers, Verena, Nielsen, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076296/ https://www.ncbi.nlm.nih.gov/pubmed/30076310 http://dx.doi.org/10.1038/s41467-018-05409-9

Ejemplares similares

Rewiring regulation on respiro-fermentative metabolism relieved Crabtree effects in Saccharomyces cerevisiae
por: Zhang, Yiming, et al.
Publicado: (2022)

A highly efficient transcriptome-based biosynthesis of non-ethanol chemicals in Crabtree negative Saccharomyces cerevisiae
por: Yao, Zhen, et al.
Publicado: (2023)

Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine
por: Qin, Jiufu, et al.
Publicado: (2015)

Profiling of Cytosolic and Peroxisomal Acetyl-CoA Metabolism in Saccharomyces cerevisiae
por: Chen, Yun, et al.
Publicado: (2012)

Scheffersomyces stipitis: a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae
por: Papini, Marta, et al.
Publicado: (2012)

Functional expression and evaluation of heterologous phosphoketolases in Saccharomyces cerevisiae
por: Bergman, Alexandra, et al.
Publicado: (2016)

Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae
por: Kocharin, Kanokarn, et al.
Publicado: (2012)

Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols
por: Ferreira, Raphael, et al.
Publicado: (2018)

Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae
por: Tippmann, Stefan, et al.
Publicado: (2017)

Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
por: Zhou, Yongjin J., et al.
Publicado: (2014)

Reconstruction and Evaluation of the Synthetic Bacterial MEP Pathway in Saccharomyces cerevisiae
por: Partow, Siavash, et al.
Publicado: (2012)

Engineering Saccharomyces cerevisiae cells for production of fatty acid-derived biofuels and chemicals
por: Hu, Yating, et al.
Publicado: (2019)

Transcriptomic response of Saccharomyces cerevisiae to octanoic acid production
por: Baumann, Leonie, et al.
Publicado: (2021)

Expression of cocoa genes in Saccharomyces cerevisiae improves cocoa butter production
por: Wei, Yongjun, et al.
Publicado: (2018)

Effects of overexpression of STB5 in Saccharomyces cerevisiae on fatty acid biosynthesis, physiology and transcriptome
por: Bergman, Alexandra, et al.
Publicado: (2019)

Impact of oleic acid as co-substrate of glucose on “short” and “long-term” Crabtree effect in Saccharomyces cerevisiae
por: Marc, Jillian, et al.
Publicado: (2013)

The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources
por: Perez-Samper, Gemma, et al.
Publicado: (2018)

Enhanced ethanol production and reduced glycerol formation in fps1∆ mutants of Saccharomyces cerevisiae engineered for improved redox balancing
por: Navarrete, Clara, et al.
Publicado: (2014)

Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae
por: Scalcinati, Gionata, et al.
Publicado: (2012)

Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion
por: Wang, Yanyan, et al.
Publicado: (2021)

Increasing cocoa butter-like lipid production of Saccharomyces cerevisiae by expression of selected cocoa genes
por: Wei, Yongjun, et al.
Publicado: (2017)

Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae
por: Teixeira, Paulo Gonçalves, et al.
Publicado: (2017)

Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production
por: Shi, Shuobo, et al.
Publicado: (2012)

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae
por: Bergman, Alexandra, et al.
Publicado: (2019)

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
por: Yu, Tao, et al.
Publicado: (2017)

Different Routes of Protein Folding Contribute to Improved Protein Production in Saccharomyces cerevisiae
por: Qi, Qi, et al.
Publicado: (2020)

Author Correction: Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
por: Yu, Tao, et al.
Publicado: (2018)

Improved production of fatty acid ethyl esters in Saccharomyces cerevisiae through up-regulation of the ethanol degradation pathway and expression of the heterologous phosphoketolase pathway
por: de Jong, Bouke Wim, et al.
Publicado: (2014)

Development of an Haa1-based biosensor for acetic acid sensing in Saccharomyces cerevisiae
por: Mormino, Maurizio, et al.
Publicado: (2021)

Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast
por: Malina, Carl, et al.
Publicado: (2021)

Transcriptional Rewiring, Adaptation, and the Role of Gene Duplication in the Metabolism of Ethanol of Saccharomyces cerevisiae
por: Sabater-Muñoz, Beatriz, et al.
Publicado: (2020)

Production of β-ionone by combined expression of carotenogenic and plant CCD1 genes in Saccharomyces cerevisiae
por: López, Javiera, et al.
Publicado: (2015)

Increasing jojoba-like wax ester production in Saccharomyces cerevisiae by enhancing very long-chain, monounsaturated fatty acid synthesis
por: Wenning, Leonie, et al.
Publicado: (2019)

An evolutionary perspective on the Crabtree effect
por: Pfeiffer, Thomas, et al.
Publicado: (2014)

CRISPR/Cas9-mediated point mutations improve α-amylase secretion in Saccharomyces cerevisiae
por: Wang, Yanyan, et al.
Publicado: (2022)

Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination
por: Groves, Benjamin, et al.
Publicado: (2016)

Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3
por: Cimini, Donatella, et al.
Publicado: (2009)

Integration of a multi-step heterologous pathway in Saccharomyces cerevisiae for the production of abscisic acid
por: Otto, Maximilian, et al.
Publicado: (2019)

Modulating DNA Repair Pathways to Diversify Genomic Alterations in Saccharomyces cerevisiae
por: Wang, Zhen, et al.
Publicado: (2022)

Identification of acetic acid sensitive strains through biosensor-based screening of a Saccharomyces cerevisiae CRISPRi library
por: Mormino, Maurizio, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_69s5f0sng3hb93m77edfnlgejn