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Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation

Human papillomavirus (HPV) entry into epithelial cells is independent of canonical endocytic pathways. Upon interaction with host cells, HPV establishes infection by traversing through an endocytic pathway that is clathrin- and caveolin-independent, but dependent on the annexin A2/S100A10 heterotetr...

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Detalles Bibliográficos
Autores principales: Taylor, Julia R., Fernandez, Daniel J., Thornton, Shantaé M., Skeate, Joseph G., Lühen, Kim P., Da Silva, Diane M., Langen, Ralf, Kast, W. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076308/
https://www.ncbi.nlm.nih.gov/pubmed/30076379
http://dx.doi.org/10.1038/s41598-018-30051-2