Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells

Replicative senescence hampers application of mesenchymal stromal cells (MSCs) because it limits culture expansion, impairs differentiation potential, and hinders reliable standardization of cell products. MSCs can be rejuvenated by reprogramming into induced pluripotent stem cells (iPSCs), which is...

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Detalles Bibliográficos
Autores principales: Göbel, Carolin, Goetzke, Roman, Eggermann, Thomas, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076311/
https://www.ncbi.nlm.nih.gov/pubmed/30076334
http://dx.doi.org/10.1038/s41598-018-30069-6

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