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Regulation of miR-181a expression in T cell aging
MicroRNAs have emerged as key regulators in T cell development, activation, and differentiation, with miR-181a having a prominent function. By targeting several signaling pathways, miR-181a is an important rheostat controlling T cell receptor (TCR) activation thresholds in thymic selection as well a...
Autores principales: | Ye, Zhongde, Li, Guangjin, Kim, Chulwoo, Hu, Bin, Jadhav, Rohit R., Weyand, Cornelia M., Goronzy, Jörg J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076328/ https://www.ncbi.nlm.nih.gov/pubmed/30076309 http://dx.doi.org/10.1038/s41467-018-05552-3 |
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