Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)

As a dioxygenase, Ten-Eleven Translocation 2 (TET2) catalyzes subsequent steps of 5-methylcytosine (5mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation, and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized....

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Detalles Bibliográficos
Autores principales: Chu, Yajing, Zhao, Zhigang, Sant, David Wayne, Zhu, Ganqian, Greenblatt, Sarah M., Liu, Lin, Wang, Jinhuan, Cao, Zeng, Tho, Jeanette Cheng, Chen, Shi, Liu, Xiaochen, Zhang, Peng, Maciejewski, Jaroslaw P., Nimer, Stephen, Wang, Gaofeng, Yuan, Weiping, Yang, Feng-Chun, Xu, Mingjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076382/
https://www.ncbi.nlm.nih.gov/pubmed/29908294
http://dx.doi.org/10.1016/j.gpb.2018.04.005

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