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Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii

BACKGROUND: Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first c...

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Autores principales: Al-Zahid, Saif, Wright, Tanwen, Reece, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076934/
https://www.ncbi.nlm.nih.gov/pubmed/30105112
http://dx.doi.org/10.1155/2018/9356243
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author Al-Zahid, Saif
Wright, Tanwen
Reece, Philip
author_facet Al-Zahid, Saif
Wright, Tanwen
Reece, Philip
author_sort Al-Zahid, Saif
collection PubMed
description BACKGROUND: Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first case report of IPT of the larynx caused by mycobacterial disease. CASE REPORT: We report a case of IPT of the larynx in an immunocompromised 81-year-old lady presenting with stridor and dysphagia with known disseminated Mycobacterium kansasii of the lungs. CONCLUSION: This case demonstrates both the clinical and histological difficulties in making the diagnosis of IPT. A high index of suspicion is needed, and the importance of a multidisciplinary approach in the work-up, diagnosis, and management is highlighted.
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spelling pubmed-60769342018-08-13 Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii Al-Zahid, Saif Wright, Tanwen Reece, Philip Case Rep Pathol Case Report BACKGROUND: Inflammatory pseudotumours (IPT) are rare benign tumours characterised by spindle-shaped histiocyte proliferation often mimicking a soft tissue sarcoma. They can occur in different parts of the body and various aetiological factors have been proposed. To our knowledge this is the first case report of IPT of the larynx caused by mycobacterial disease. CASE REPORT: We report a case of IPT of the larynx in an immunocompromised 81-year-old lady presenting with stridor and dysphagia with known disseminated Mycobacterium kansasii of the lungs. CONCLUSION: This case demonstrates both the clinical and histological difficulties in making the diagnosis of IPT. A high index of suspicion is needed, and the importance of a multidisciplinary approach in the work-up, diagnosis, and management is highlighted. Hindawi 2018-07-09 /pmc/articles/PMC6076934/ /pubmed/30105112 http://dx.doi.org/10.1155/2018/9356243 Text en Copyright © 2018 Saif Al-Zahid et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Al-Zahid, Saif
Wright, Tanwen
Reece, Philip
Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_full Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_fullStr Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_full_unstemmed Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_short Laryngeal Inflammatory Pseudotumour Secondary to Mycobacterium kansasii
title_sort laryngeal inflammatory pseudotumour secondary to mycobacterium kansasii
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076934/
https://www.ncbi.nlm.nih.gov/pubmed/30105112
http://dx.doi.org/10.1155/2018/9356243
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