Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle

Skeletal muscle is ideal for passive vaccine administration as it is easily accessible by intramuscular injection. Recombinant adeno-associated virus (rAAV) vectors are in consideration for passive vaccination clinical trials for HIV and influenza. However, greater human skeletal muscle transduction...

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Detalles Bibliográficos
Autores principales: Paulk, Nicole K., Pekrun, Katja, Charville, Gregory W., Maguire-Nguyen, Katie, Wosczyna, Michael N., Xu, Jianpeng, Zhang, Yue, Lisowski, Leszek, Yoo, Bryan, Vilches-Moure, Jose G., Lee, Gordon K., Shrager, Joseph B., Rando, Thomas A., Kay, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077147/
https://www.ncbi.nlm.nih.gov/pubmed/30101152
http://dx.doi.org/10.1016/j.omtm.2018.06.001

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